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An outbreak of a mystery strain of encephalitis has killed nearly 500 children in northern India this year and seems to be getting worse, doctors said Thursday.

Doctors in Uttar Pradesh state, the center of the outbreak, have been unable to identify the strain of the disease, which has affected only children, killing 484 of them since the beginning of the year, said state Health Minister Anant Kumar Mishra.

And the outbreak is spreading quickly, doctors said.

“There has been a sudden spurt in encephalitis cases over the last month. Over 100 children have died and encephalitis cases are pouring in from eastern parts of the state,” said Dr. Akhilesh Srivastava, a senior government doctor.

Outbreaks of mosquito-borne encephalitis are common in Uttar Pradesh, a state of 180 million people where most public health facilities are out of reach for the overwhelmingly poor population.

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